What is an Immunodeficiency?
An immunodeficiency is a disease or disorder in which an individual’s immune system does not produce a sufficient response to fight off infections, viruses, and other potentially harmful pathogens. An immunodeficiency can be present at birth, due to a genetic defect. This is known as a primary immunodeficiency. There are more than 150 different types of primary immunodeficiencies. An immunodeficiency can also develop during an individual’s lifetime. This is known as a secondary immunodeficiency. Secondary immunodeficiencies can occur as the result of certain medications such as chemotherapy and systemic steroids, illnesses (like HIV/AIDS), severe burns or malnutrition.
What are Common Symptoms of an Immunodeficiency?
Signs of an immunodeficiency include frequent or recurring infections and diseases, such as bronchitis, pneumonia, or sinus infections. Digestive disorders, delayed development, and autoimmune disorders, such as type 1 diabetes, rheumatoid arthritis and lupus, are also associated with immunodeficiency.
How is an Immunodeficiency Diagnosed?
Dr. Min begins every diagnosis with a complete review of your medical history and a thorough physical examination. In addition, blood testing may be conducted to evaluate your immune system.
What is Immunoglobulin Therapy?
Individuals suffering from immunodeficiency diseases have successfully managed their condition with immunoglobulin replacement therapy for more than 50 years. This life-changing therapy involves supplementing patients with blood from healthy donors. The blood is processed and purified and then delivered to the patient under the skin or through an IV line into a vein or an injection under the skin (subcutaneous infusions). IV delivery allows for larger amounts of blood to be transferred and is therefore typically administered every few weeks, while subcutaneous infusions are usually needed 1-2 times per week. Subcutaneous infusions can sometimes be administered at home. Treatment schedules are individualized and modified as necessary. Immunoglobulin replacement therapy has a superior safety record and is often a lifelong treatment.
